Weight loss inactivated bacteria powder (Lactobacillus rhamnosus FSHMX12)
Lactobacillus rhamnosus FSHMX12 functions based on the regulation of brown fat lipid metabolism and thermogenesis.
Down-regulates the expression of fat synthase gene Fasn, inhibits lipid synthesis in the liver, increases the expression of Atgl and Hsl encoding genes for key catabolic enzymes of lipid metabolism in the liver, promotes the production of free fatty acids, and provides a substrate for non-shivering thermogenesis . Elevated expression of brown fat peroxisome proliferator-activated receptor (PPAR) gene Ppar-γ and peroxisome proliferator-activated receptor-γ coactivator-1α gene Pgc1α increased non-shivering in brown fat Sexual heat production. Significantly increased the proportion of small adipocytes (diameter ≤50µm) in epididymal white fat, decreased the proportion of large adipocytes (diameter ≥70µm), effectively reduced the number and volume of lipid droplets in brown adipose tissue, alleviated fat accumulation, and maintained Normal morphology and function of brown adipose tissue.
Lactobacillus plantarum CN2018
Patent name: A Lactobacillus plantarum CN2018 resistant to Helicobacter pylori infection and its application It is a patent probiotics with excellent performance that was isolated and screened out from Chinese traditional fermented food by researchers of National Functional Food Engineering Technology Research Center of Jiangnan University in 2008. The strain can grow in artificial gastric juice with pH2.5 and in the medium with bile salt concentration of 0.2%, indicating that the strain can maintain high activity in the intestinal tract of the host. Lactobacillus plantarum CN2018 has the strongest ability to inhibit the growth of Helicobacter pylori and can significantly reduce the urease activity of helicobacter pylori. Through the establishment of helicobacter pylori infection animal model, it was found that Lactobacillus plantarum CN2018 could significantly alleviate helicobacter pylori infection in mice, and the anti-Helicobacter pylori IgG antibody level decreased. The content of Helicobacter pylori in gastric tissue was decreased by intervention of Helicobacter pylori colonization. And prevent pathological changes of gastric tissue. At the same time, it can reduce the content of helicobacter pylori in the mouth, adjust the balance of oral flora, and promote oral health. Both live and dead Lactobacillus plantarum CN2018 had inhibitory effect on H. pylori. From the size of the inhibition zone, CN2018, fermentation liquid and dead bacteria all had certain inhibitory effect on H. pylori. The urease activity of Helicobacter pylori significantly decreased after CN2018, fermentation broth and dead bacteria treated h. pylori for 2 hours, and the ability of H. pylori to adsorb intestinal epithelial cells significantly decreased.